Gifu University (Japan)
Dr. Hiromune Ando completed his PhD at Gifu University in 1999. After postdoctoral research at RIKEN and Gifu University in Japan, he was promoted to Assistant Professor at Gifu University in 2003. In 2008, he was concurrently appointed as an Associate Professor at the Institute for Integration of Cell-Material Sciences (Kyoto University) and Gifu University. In 2017, he was promoted to Full Professor at the Center for Highly Advanced Integration of Nano and Life Sciences (Gifu University). In 2021, he was appointed as the Vice Director of the Institute for Glyco-core Research (iGCORE) of Gifu University. His current research focus is on organic synthesis of complex glycoconjugates and chemical biology of glycan-enriched cell membrane domains.
Dr. Ando is a Director of the Japanese Society of Carbohydrate Research (JSCR) and a Board Member of the Japan Consortium for Glycobiology & Glycotechnology (JCGG). He was awarded the JSCR Award for Young Scientist, the Incentive Award for Young Scientist from the Society of Synthetic Organic Chemistry, and the Encourage Award of Young Scientists from the Japan Society for Bioscience, Biotechnology and Agrochemistry. Recently, he received the e-TCR Award 2018 from the Trends in Carbohydrate Research and the 2019 Young Investigator Award from the Journal of Carbohydrate Chemistry. He is a member of the editorial board of the Journal of Carbohydrate Chemistry.
University of California, Davis (USA)
Dr. Xi Chen is a Professor at the Department of Chemistry in the University of California-Davis. She received her B.S. degree in Chemistry from Xiamen University in 1994 and her Ph.D. degree in Biological/Organic Chemistry from Wayne State University in 2000. She worked at Neose Technologies, Inc. for two and a half years before joining the Department of Chemistry at the University of California, Davis as an Assistant Professor in August 2003. She was promoted to Associate Professor in 2008 and to Professor in 2011.
Her research interests are at the interface of chemistry and biology with a focus on glycoscience. Her group strives to understand carbohydrate-related biological processes in the areas of cancer, inflammation, immunology, viral and bacterial infection. The current research focuses are: 1) developing chemoenzymatic approaches for synthesizing structurally defined complex glycans and glycoconjugates; 2) studying carbohydrate-protein/cell interactions and exploring the functions and the applications of carbohydrates; 3) collaborative crystal structure and mutagenesis studies of glycosyltransferases and other carbohydrate biosynthetic enzymes; and 4) designing and synthesizing sialidase substrates and inhibitors.
University of Milan (Italy)
Dr. Chiricozzi is Associate Professor of Biochemistry at the Department of Medical Biotechnology and Translational Medicine, University of Milan, Italy. She obtained her PhD in Biochemistry from the University of Milan, where her research focused on the role of sphingolipids as signaling molecules in health and disease.
Her scientific activity is centered on membrane lipid biology and neurochemistry, with particular emphasis on the neurotrophic and neuroprotective properties of ganglioside GM1 and its oligosaccharide moiety. Her work has contributed to redefining the role of ganglioside oligosaccharides in plasma membrane signaling, demonstrating their direct involvement in TrkA receptor activation, neuronal differentiation, and neuroprotection. These findings have opened new therapeutic perspectives for neurodegenerative disorders, particularly Parkinson’s disease, leading to patented inventions and translational research projects.
Dr. Chiricozzi has authored over 40 peer-reviewed publications and actively collaborates with national and international research groups. She is the Principal Investigator of several competitive research grants and leads a multidisciplinary research team focused on the development of glycan-based therapeutic strategies for neurological diseases. In parallel, she is deeply involved in undergraduate and postgraduate teaching in medical and biotechnology programs and in the supervision of PhD students and postdoctoral fellows.
Case Western Reserve University (USA)
Dr. Cobb completed his undergraduate BS degree at the University of Oklahoma in Biochemistry in 1995, and his PhD at Washington University School of Medicine in St. Louis in Biochemistry in 2001. Upon graduation, he joined the laboratory of Dennis L. Kasper, MD at Harvard Medical School as a postdoctoral fellow. He remained there until being recruited to Case Western Reserve University (CWRU) School of Medicine in 2005.
Today, he is the Michael E. Lamm Professor of Pathology and currently serves as the Director of the CWRU PhD Immunology Training Program (ITP) and is a steering committee member for the Consortium for Functional Glycomics. He is on the editorial boards of both Glycobiology and the Journal of Biological Chemistry, and is active in both the Society for Glycobiology and the American Association of Immunologists.
Scientifically, Dr. Cobb is a leader in research at the interface of glycobiology and immunology through investigating the impact of glycans on immune regulation. His recent work has focused on the regulation of IgG sialylation and the role of Siglec-2 (CD22) on macrophage function.
Utrecht University (the Netherlands)
My scientific vision is to redefine how we understand virus–host interactions by uncovering the molecular features of viral engagement with host cell surface glycans. I aim to move the field beyond simplified receptor concepts toward a mechanistic and biologically relevant framework that explains viral host adaptation, antigenic evolution, and zoonotic emergence.
I am an Associate Professor in Chemical Biology & Drug Discovery at Utrecht University, where I lead an interdisciplinary research program integrating virology, glycobiology, structural biology, and chemical biology. My PhD training in virology and postdoctoral work at The Scripps Research Institute established a strong foundation in influenza virus glycoprotein biology and receptor specificity. These experiences shaped my long-term ambition to connect molecular recognition at the virus–glycan interface to viral evolution and immune escape at the organismal level.
My ERC Starting Grant enabled me to establish an independent research line that combined chemo-enzymatic glycan synthesis, glycan arrays, tissue binding assays, and structural approaches to reveal previously unrecognized principles of influenza virus receptor usage. Building on this foundation, my ERC Consolidator Grant research vision focuses on integrating receptor binding, antigenic drift, and immune pressure into a unified conceptual framework explaining influenza virus evolution across hosts and tissues. Through ERC Proof of Concept funding, I seek to translate fundamental discoveries into innovative tools and strategies that support antiviral development, vaccine design, and pandemic preparedness.
Looking ahead, my goal is to establish a globally leading research program that bridges chemistry and virology to deliver novel concepts on infectious disease research and public health.
Griffith University (Australia)
Professor Michael Jennings is an NHMRC Leadership Investigator and Deputy Director of the Institute for Glycomics, Griffith University. He is an internationally recognised leader in infectious diseases research with a focus on glycoscience. His current research investigates the molecular basis of glycointeractions between a range of pathogens and the human host, and the application of this information to develop strategies for diagnostics, prevention and treatment of infectious disease. His recent work has branched into the glycobiology of cancer with a view to improve early diagnosis of disease.
University of California, San Diego (USA)
Dr “Mandy” Lewis received her Ph.D. at the University of California San Diego where she studied the biochemical and genetic basis of capsular polysaccharide modifications in the neonatal pathogen Group B Streptococcus and was awarded the most outstanding dissertation in biology and chemistry in her graduating class. She remained at UC San Diego for postdoctoral training at the intersection of glycobiology and bacterial pathogenesis, later founding her own lab at Washington University School of Medicine in St. Louis. At WashU, she built a research program connecting glycobiology, microbiology, and women's health. Since then, her research has been recognized by several faculty career awards and grants from the National Institutes of Health. She received tenure in the Molecular Microbiology department and was named a Distinguished Investigator at Washington University. In 2020, she returned to UC San Diego as a tenured Professor in the Department of Ob/Gyn and Reproductive Sciences. Dr Lewis became Co-Director of the Glycobiology Research and Training Center at UCSD in 2022. Her research seeks to define how members of the vaginal microbiota interact to produce features of disease in the urinary and genital systems, and in particular, how the biology of glycans may underpin these relationships.
University of Alberta (Canada)
As a Canada Research Chair in Glycoimmunology and the Lemieux Chair of Carbohydrate Chemistry, my laboratory at the University of Alberta is developing and applying chemical, biochemical, and genetic approaches to study and modulate immune responses through a family of glycan-binding proteins called Siglecs. Rooted in a biochemical understanding of how glycans have the potential to modulate the function of glycan-binding proteins, I am leveraging my knowledge as an immunologist to further elucidate roles Siglecs in immune responses under diseased conditions. I am particularly interested in genetic links between Siglecs and human disease and modeling this in mouse models. An important aspect of this work flows out of our development of biochemical tools to study Siglec ligands in cells and tissues. The ultimate goal of my laboratory is to better understand the immunomodulatory properties of Siglecs in order to modulate immune cells for improving human health.
CIC bioGUNE (Spain)
I obtained my BSc in Biochemistry from the University of the Basque Country (UPV/EHU, Spain) and completed my PhD in Molecular Biology and Biomedicine (2011–2015), where I developed a strong foundation in molecular and cellular biology. I subsequently pursued postdoctoral training at The Hospital for Sick Children (SickKids, Canada), focusing on the structural and functional characterization of B-cell surface receptors with immunotherapeutic potential.
In 2019, I joined CIC bioGUNE (Spain) as a Research Fellow and successfully completed a five-year tenure-track period (2019–2024). In 2024, I established my independent research group, the Cancer Glycoimmunology Lab. My laboratory is embedded within a highly collaborative and interdisciplinary research environment with strong expertise in structural biology, immunology, and cancer research.
My research program aims to elucidate the molecular mechanisms governing antibody and glycan-binding receptor function, with a particular focus on Siglec glycoimmune checkpoint receptors. By integrating structural biology, biophysical methods, and molecular engineering, my work dissects antibody–Siglec and glycan–Siglec interactions at atomic and mechanistic levels. This knowledge enables the rational development of next-generation therapeutic molecules, including engineered antibodies and glycan-based modulators. In parallel, my laboratory develops and characterizes antibodies targeting tumor-associated glycans, contributing directly to innovative cancer immunotherapy strategies.
The Scripps Research Institute (USA)
Dr. Peng Wu received his doctorate from the Scripps Research Institute in 2005 under the guidance of Professor K. Barry Sharpless. His graduate studies with Prof. Sharpless laid the foundation for the development of click chemistry, which was recognized by the 2022 Nobel Prize in Chemistry. From August 2005 to September 2008, he was a postdoctoral fellow in the group of Professor Carolyn R. Bertozzi at the University of California, Berkeley. At Berkeley, he combined his interests in bioorthogonal chemistry and biotechnology by developing a method for site-specific modification of monoclonal antibodies using a genetically encoded aldehyde tag. This technology was licensed to Catalent Biologics and developed into a platform that is now known as the SMARTAG®. The research in the Wu lab integrates synthetic chemistry with glycobiology to explore the cellular and molecular mechanisms that control immune responses toward cancer and human pathogens. FucoID, a genetic engineering-free labeling technique developed by the Wu lab, provides the first technology to identify the entire repertoire of tumor antigen-specific T cells for cancer immunotherapy. His recent prized include the ACS Horace S. Isbell Award in 2020, the RSC Horizon Prize in 2021 and the SFG Glycobiology Significant Achievement Award in 2021.